CIDP: A Clinical Diagnosis in Search of a Disease

  • Investigate CIDP as a clinical syndrome diagnosed by appearance, not cause
  • Examine how biological heterogeneity creates problems – variable placebo response, diluted effects, uninterpretable results – because functional endpoints don’t capture immunologic activity
  • Propose the path forward in CIDP: immunophenotyping and biomarker-stratified trials to target defined mechanisms precisely